Did you ever happen to break a tooth while chewing down on something? This is a common issue for many people which requires a trip to the dentist and is usually fixed with a dental filling. Nevertheless, you need to understand that scientists have found a new way which seek to replace tooth fillings in the future.
Just recently, scientists from the King’s College of London conducted a research where they discovered that a common Alzheimer’s drug can stimulate the development of stem cells in the oral pulp and create new dentin in the teeth, which makes oral fillings obsolete. In this way, the drug can make your teeth fix themselves!
When a tooth is damaged by an infection or breakage, a thin layer of dentin grows around the rupture in order to secure the area and seal off the internal tissue. Nevertheless, this layer cannot protect deep breaks and ruptures, which is why they’re closed off with artificial fillings. Nevertheless, even fillings don’t always work– often, an infection may affect the root under the filling, which has to be replaced again and again till the tooth dies off and has to be removed.
Thankfully, this new procedure can help the tooth repair work itself. The process includes putting a little sponge of naturally biodegradable collagen into the hole– this collagen is also the base of a common Alzheimer’s disease drug which inhibits the activity of the GSK-3 enzyme. This enzyme prevents the formation of dentin, but as it’s action is blocked, the collagen sponge manages to stimulate the production of large quantities of dentin which closes the hole in your tooth.
This is a revolutionary discovery which provides hope for the future of oral restoration. Although it has actually only been tested on mice, and there have been no human trials yet, scientists are pretty optimistic and believe that the treatment could help even broken teeth regrow themselves. If the GSK-3 inhibitor is approved for human trials, we can look forward to no more fillings and the dreadful sound of the oral hand piece.